SULTRINOR

Sultrinor injectable solution is a sterile solution formulated as injectable preparation composed of trimethoprim and sulphadiazine composed of trimethroprim and silphadiazine. The action of the combination proved to be bactericidal, whereas the components separately were only bacteriostatic in action. Sulphonamides actas an analogue for para-aminobenzoic acid, (PABA) which itself a part of vitamin, folic acid.
in organisms that synthesis their own folic acid, sulphonamides as sulphadiazine acts by blocking the synthesis of folic acid.
Sulphonamides are active agianst bacteria but not against higher organisms as bacteria synthesis their folic acid whereas higher animals or higher organisms obtained folic acid from the diet.

SULTRINOR injection is indicated for the treatment of infections caused by microorganism, susceptible to trimethoprim and or sulphadiazine affecting the respiratory urogenital and gastro-intestine tract.

SULTRINOR injection is a distinctive drug against a wide range of Gram-positive and Gram-negative bacteria such as E.coli, Salmonella, Klebsiella, Brucella, Corynebacterium pyogens, Pasteurella, Staphylococcus, strepteococcus, Enterobacter and Haemophilus.